- 7 lessons
- 1 quizzes
- 10 week duration
Module 3
EFFECT OF VACCINATION
Some studies revealed that the first rotavirus vaccine has launched the schedule for national childhood immunization, which was made compulsory in all hospitalizations for each student who has symptoms of rotavirus. And the vaccine was exported to all over the country as well as lunched in the market. According to the Woode G et al., reports, all the collected samples from rich and poor countries, the report suggested that rich country children are not eligible for the rotavirus vaccination process because of the herd immunity, but herd immunity or
indirect protection for vaccination was not observed in the poor countries. The reason for this situation was not clear until now.
According to the national schedule for immunization, statistical graph shows decrease in the rotavirus infection patient cases because the vaccine was launched, and after vaccination the spreading of disease was controlled worldwide. After the vaccine came to existence, the cases were decreased. The rotavirus disease was observed in the children’s and old age peoples because the people were coming in the contact of infected people. After the
vaccination was launched, it was reported that different rotavirus strains contain diverse genotype based variation in case of vaccination. Rotavirus G2P strains were observed in many countries, where they launched G2 genotype based pentavalent rotavirus vaccine for effective results. This strain was initially noticed in Brazil; where G2Pinduced diarrhoea showed an effective reaction against the monovalent G1P rotavirus vaccine consequently preventing the disease. Moreover, the differences between the indigenous variations or vaccine induced selection pressure (rotavirus genotypes) are unclear. To monitoring genotypes, whole genomic
characterization of enrolling and circulating strains of rotavirus before and after introduction of vaccine that help assess for evolution of the rotavirus genome.