Patchdock-Working concept of molecular docking

Methodology

The molecular docking algorithm is another level segment in the bioinformatic techniques or computational biology. According to this algorithms, the two molecules (receptor and ligand), which converts their surfaces into Patches with respective surface structures or models.

– analyze the exact molecular surface of the molecule and segment the algorithms to check the patches.

– with subjected to Algorithms, define patches will be recovered.

– in last step, discard the all complexes structure with non-defined interaction to molecule of the receptor to the molecules of the ligands.